Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPINK2Serine protease inhibitor Kazal-type 2. (87 aa)    
Predicted Functional Partners:
PMPCA
Mitochondrial-processing peptidase subunit alpha.
    
   0.529
SPINK1
Serine protease inhibitor Kazal-type 1.
      
 0.496
KLK4
Kallikrein-4 isoform X1.
    
 0.487
NUDT8
Nucleoside diphosphate-linked moiety X motif 8.
    
   0.466
ENSPPRP00000015338
Serine protease inhibitor Kazal-type 10/11.
      
 0.447
SPINK13
Serine peptidase inhibitor, Kazal type 13 (putative).
      
 0.423
SERPINE2
Glia-derived nexin isoform X1.
     
 0.421
SPINK4
Serine protease inhibitor Kazal-type 4 isoform X1.
  
   
 0.415
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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