Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIRREL3Kin of IRRE-like protein 3 isoform X1. (778 aa)    
Predicted Functional Partners:
NPHS1
Nephrin.
   
 0.941
TJP1
Tight junction protein ZO-1 isoform X1.
    
 0.737
NPHS2
Podocin.
    
 0.626
NLGN2
Neuroligin-2.
    
 0.609
NLGN3
Neuroligin-3 isoform X1.
    
 0.565
PPP4R4
Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1.
     
 0.564
BRINP2
BMP/retinoic acid-inducible neural-specific protein 2 isoform X1.
   
  
 0.563
HTR2C
5-hydroxytryptamine receptor 2C isoform X1.
   
 
 0.560
CNTN5
Contactin 5.
   
 0.556
ERGIC1
Endoplasmic reticulum-Golgi intermediate compartment protein 1.
      
 0.542
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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