Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
WRAP53Telomerase Cajal body protein 1. (536 aa)    
Predicted Functional Partners:
DKC1
H/ACA ribonucleoprotein complex subunit 4.
    
 0.997
NHP2
H/ACA ribonucleoprotein complex subunit 2.
    
 0.991
GAR1
H/ACA ribonucleoprotein complex subunit 1.
    
 0.990
NOP10
H/ACA ribonucleoprotein complex subunit 3.
    
 0.987
TERT
Telomerase reverse transcriptase isoform X1.
    
 0.948
TRUB1
Probable tRNA pseudouridine synthase 1.
    
 0.824
CCT2
T-complex protein 1 subunit beta.
    
 0.812
TINF2
TERF1-interacting nuclear factor 2 isoform X1.
     
 0.797
BRIP1
LOW QUALITY PROTEIN: Fanconi anemia group J protein.
   
 
 0.793
USP11
LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 11.
    
 0.790
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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