Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CREB3L2Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1. (520 aa)    
Predicted Functional Partners:
CREB3
Cyclic AMP-responsive element-binding protein 3.
    
 0.934
RPS6KA5
Ribosomal protein S6 kinase alpha-5 isoform X1.
    
  0.896
CRTC2
CREB-regulated transcription coactivator 2-like.
    
 0.895
MAPK1
Mitogen-activated protein kinase 1/3.
     
 0.894
PRKACB
CAMP-dependent protein kinase catalytic subunit beta isoform X1.
     
  0.894
CREB1
Cyclic AMP-responsive element-binding protein 1 isoform X1.
    
 0.884
ENSPPRP00000023757
annotation not available
    
 0.882
CREB3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1.
    
 0.878
ATF6B
Cyclic AMP-dependent transcription factor ATF-6 beta isoform X1.
    
 0.872
CREM
CAMP-responsive element modulator isoform X1.
    
 0.869
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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