Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RASGRP2RAS guanyl-releasing protein 2. (594 aa)    
Predicted Functional Partners:
RAP1B
Ras-related protein Rap-1B.
    
 0.931
RAP1A
Ras-related protein Rap-1A isoform X1.
    
 0.930
KRAS
GTPase KRas isoform X1.
    
 0.909
CACNG8
LOW QUALITY PROTEIN: voltage-dependent calcium channel gamma-8 subunit.
    
 0.903
MRAS
Ras-related protein M-Ras isoform X1.
    
 0.902
CACNG3
Voltage-dependent calcium channel gamma-3 subunit isoform X1.
   
 0.898
RASGRP1
RAS guanyl-releasing protein 1 isoform X1.
     
 0.898
CACNA1B
Voltage-dependent N-type calcium channel subunit alpha-1B isoform X1.
   
 
  0.895
CACNA1S
Voltage-dependent L-type calcium channel subunit alpha-1S.
   
 
  0.895
CACNA2D2
Voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1.
     
 0.895
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.