STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MFGE8Milk fat globule-EGF factor 8 protein. (388 aa)    
Predicted Functional Partners:
ITGAV
Integrin alpha V.
    
 0.947
ITGB5
Integrin beta-5 isoform X1.
    
 0.808
ITGA2B
Integrin alpha-IIb.
    
 0.614
ITGA5
Integrin subunit alpha 5.
    
 0.606
ITGA8
Integrin alpha 8.
    
 0.606
NUP214
Nuclear pore complex protein Nup214 isoform X1.
   
 0.583
PRDM5
PR domain zinc finger protein 5 isoform X1.
    
 
 0.562
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif 13.
    
 0.528
NUP98
Nuclear pore complex protein Nup98-Nup96 isoform X1.
    
 0.528
NUP43
Nuclear pore complex protein Nup43.
    
 0.524
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.