Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TIAM2T-lymphoma invasion and metastasis-inducing protein 2 isoform X1. (1669 aa)    
Predicted Functional Partners:
PARD3
Partitioning defective 3 homolog isoform X1.
    
 0.868
CD44
CD44 molecule (Indian blood group).
    
 0.816
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.
   
 
 0.787
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.
   
 
 0.787
PIK3CD
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta.
   
 
 0.787
MRAS
Ras-related protein M-Ras isoform X1.
    
 0.778
RASSF1
Ras association domain-containing protein 1 isoform X1.
     
 0.752
RAC2
Rac family small GTPase 2.
    
 0.713
RAC3
Rac family small GTPase 3.
    
 0.713
RAC1
Ras-related C3 botulinum toxin substrate 1 isoform X1.
    
 0.713
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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