Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAMR1Inactive serine protease PAMR1 isoform X1. (720 aa)    
Predicted Functional Partners:
SMIM12
Small integral membrane protein 12.
    
 0.634
ENDOU
Poly(U)-specific endoribonuclease isoform X1.
      
 0.559
AAMDC
Mth938 domain-containing protein.
      
 0.543
CLPTM1L
Cleft lip and palate transmembrane protein 1-like protein isoform X1.
    
 
 0.543
RNF151
RING finger protein 151 isoform X1.
      
 0.539
SLC1A2
Solute carrier family 1 (glial high affinity glutamate transporter), member 2.
   
 
 0.533
SH3D21
SH3 domain-containing protein 21 isoform X1.
      
 0.522
TCAIM
T-cell activation inhibitor, mitochondrial.
      
 0.520
LRRC40
Leucine-rich repeat-containing protein 40 isoform X1.
    
 0.516
ZC3H8
Zinc finger CCCH-type containing 8.
      
 0.515
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.