Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SIRT2NAD-dependent protein deacetylase sirtuin-2 isoform X1. (390 aa)    
Predicted Functional Partners:
SIRT5
NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X1.
  
0.964
SIRT4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial isoform X1.
  
 
0.961
SIRT1
NAD-dependent protein deacetylase sirtuin-1 isoform X1.
   
 0.953
SIRT6
Sirtuin 6.
     
 0.939
NAMPT
Nicotinamide phosphoribosyltransferase.
     
 0.931
SIRT7
NAD+-dependent protein deacetylase sirtuin 7.
     
 0.921
NADSYN1
Glutamine-dependent NAD(+) synthetase isoform X1.
    
 0.912
SARM1
Sterile alpha and TIR motif-containing protein 1 isoform X1.
     
 0.910
NADK
NAD kinase isoform X1.
  
 
 0.910
NUDT12
Peroxisomal NADH pyrophosphatase NUDT12.
   
 0.909
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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