STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOD2Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1040 aa)    
Predicted Functional Partners:
RIPK2
Receptor-interacting serine/threonine-protein kinase 2.
   
 0.998
ATG16L1
Autophagy-related protein 16-1 isoform X1.
    
 0.991
ERBIN
Erbb2-interacting protein.
    
 0.941
MAVS
Mitochondrial antiviral-signaling protein isoform X1.
    
 0.939
ATG5
Autophagy protein 5 isoform X1.
    
 0.932
ATG12
Ubiquitin-like protein ATG12.
    
 0.918
AAMP
Angio-associated migratory cell protein isoform X1.
     
 0.911
XIAP
E3 ubiquitin-protein ligase XIAP.
    
 0.901
SUGT1
Suppressor of G2 allele of SKP1.
    
 0.888
CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD isoform X1.
    
 0.871
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.