close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB113Defensin beta 113. (74 aa)    
Predicted Functional Partners:
DEFB124
Beta-defensin 124.
  
  
 0.865
DEFB121
Beta-defensin 121.
     
 0.857
ENSPPRP00000029519
annotation not available
  
  
 0.774
DEFB123
Beta-defensin 123.
     
 0.758
DEFB135
Beta-defensin 135.
  
  
 0.748
DEFB129
Beta-defensin 129.
     
 0.739
ENSPPRP00000001186
annotation not available
     
 0.685
LOC109257851
Beta-defensin 130-like.
  
  
  0.675
DEFB116
LOW QUALITY PROTEIN: beta-defensin 116.
     
 0.665
LOC109260746
Sperm-associated antigen 11-like.
   
  
 0.648
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.