close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EBF2Transcription factor COE2 isoform X1. (575 aa)    
Predicted Functional Partners:
UFD1
Ubiquitin fusion degradation protein 1 homolog.
    
 
 0.625
PLAA
Phospholipase A-2-activating protein isoform X1.
    
   0.597
YOD1
YOD1 deubiquitinase.
    
   0.597
LHX9
LIM/homeobox protein Lhx9 isoform X1.
   
 
 0.470
LHX2
LIM/homeobox protein Lhx2.
   
 
 0.436
DAPP1
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide.
     
 0.433
VCP
Transitional endoplasmic reticulum ATPase isoform X1.
   
 0.426
SPATA5
Spermatogenesis-associated protein 5 isoform X1.
   
 0.426
SPATA5L1
Spermatogenesis-associated protein 5-like protein 1 isoform X1.
   
 0.426
LRRC17
Leucine-rich repeat-containing protein 17.
      
 0.408
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.