Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EBF2Transcription factor COE2 isoform X1. (575 aa)    
Predicted Functional Partners:
UFD1
Ubiquitin fusion degradation protein 1 homolog.
    
 
 0.552
EEF1G
Elongation factor 1-gamma.
    
   0.551
HNRNPU
Heterogeneous nuclear ribonucleoprotein U isoform X1.
     
 0.536
SCD5
Stearoyl-CoA desaturase (Delta-9 desaturase).
   
 
 0.511
SCD
Stearoyl-CoA desaturase (Delta-9 desaturase).
   
 
 0.511
PLAA
Phospholipase A-2-activating protein isoform X1.
    
   0.501
YOD1
YOD1 deubiquitinase.
    
   0.501
LHX2
LIM/homeobox protein Lhx2.
   
 
 0.492
ETV3
ETS translocation variant 3-like isoform X1.
   
  
 0.476
ZNF423
Zinc finger protein 423 isoform X1.
   
 0.474
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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