Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PPA1Inorganic pyrophosphatase. (289 aa)    
Predicted Functional Partners:
PPA2
Inorganic pyrophosphatase 2, mitochondrial isoform X1.
   
 0.994
ATP5PO
F-type H+-transporting ATPase subunit O.
   
 
 0.944
ATP5F1A
F-type H+-transporting ATPase subunit alpha.
   
 
 0.942
LHPP
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform X1.
     
 0.942
ATP5F1C
ATP synthase subunit gamma, mitochondrial isoform X1.
   
 
 0.940
ATP5F1B
ATP synthase subunit beta, mitochondrial isoform X1.
   
 
 0.928
ATP6V1B2
V-type proton ATPase subunit B, brain isoform.
   
 
 0.922
ATP6V1B1
V-type proton ATPase subunit B, kidney isoform.
   
 
 0.922
ATP4A
Potassium-transporting ATPase alpha chain 1.
     
 0.921
ATP12A
Potassium-transporting ATPase alpha chain 2.
     
 0.921
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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