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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC36Coiled-coil domain-containing protein 36. (591 aa)    
Predicted Functional Partners:
PRR35
Proline rich 35.
      
 0.739
RRP36
Kelch domain-containing protein 3.
      
 0.739
SIPA1L2
Signal-induced proliferation-associated 1-like protein 2 isoform X1.
      
 0.708
KBTBD12
Kelch repeat and BTB domain-containing protein 12 isoform X1.
      
 0.621
RAB11FIP3
RAB11 family interacting protein 3.
      
 0.619
C3orf62
Uncharacterized protein C3orf62 homolog isoform X1.
      
 0.613
TRAPPC6B
Trafficking protein particle complex subunit 6B.
      
 0.610
KCNG3
Potassium voltage-gated channel subfamily G member 3 isoform X1.
      
 0.606
METRN
Meteorin.
      
 0.606
SEZ6L
Seizure 6-like protein.
   
  
 0.604
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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