STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATRXTranscriptional regulator ATRX isoform X1. (2478 aa)    
Predicted Functional Partners:
DAXX
Death domain-associated protein 6 isoform X1.
    
 0.998
RAD51
DNA repair protein RAD51 homolog 1.
    
 0.979
MECP2
Methyl CpG binding protein 2.
    
 0.880
SUPT16H
FACT complex subunit SPT16.
   
 
 0.860
PHIP
PH-interacting protein isoform X1.
   
 0.858
RAD50
DNA repair protein RAD50 isoform X1.
  
 
 0.852
SMC5
Structural maintenance of chromosomes protein 5 isoform X1.
  
 0.843
MRE11
Double-strand break repair protein MRE11A isoform X1.
  
 
 0.840
THOC2
THO complex subunit 2 isoform X1.
   
 
 0.828
SSRP1
Structure-specific recognition protein 1.
    
 
 0.827
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.