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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDC42EP1Cdc42 effector protein 1. (367 aa)    
Predicted Functional Partners:
SLC24A3
Solute carrier family 24 (sodium/potassium/calcium exchanger), member 3.
      
 0.632
STXBP6
Syntaxin-binding protein 6 isoform X1.
      
 0.629
RAC1
Ras-related C3 botulinum toxin substrate 1 isoform X1.
    
 0.623
RAC2
Rac family small GTPase 2.
    
 0.603
RHOG
Rho-related GTP-binding protein RhoG.
    
 0.603
RHOQ
Rho-related GTP-binding protein RhoQ isoform X1.
    
 0.591
ENSPPRP00000015553
annotation not available
    
 0.561
ENSPPRP00000025718
annotation not available
    
 0.561
CDC42
Cell division control protein 42 homolog.
    
 0.561
CDH18
Cadherin-18 isoform X1.
     
 0.529
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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