STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A2ML1Alpha-2-macroglobulin-like protein 1. (1446 aa)    
Predicted Functional Partners:
CBX8
Chromobox protein homolog 8.
    
 0.745
CBX4
Chromobox 4.
    
 0.742
CBX2
Chromobox protein homolog 2.
    
 0.732
LOC109255088
Coiled-coil domain-containing protein 92.
      
 0.714
PPL
Periplakin isoform X1.
   
  
 0.705
CACNA1G
Voltage-dependent T-type calcium channel subunit alpha-1G isoform X1.
   
  
 0.704
EVPL
Envoplakin.
   
  
 0.699
FBXL21P
F-box and leucine-rich repeat protein 21.
    
 
 0.647
BMI1
Polycomb group RING finger protein 4.
    
 0.622
PCGF2
Polycomb group RING finger protein 2 isoform X1.
    
 0.622
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.