STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PANX2Pannexin 2/3. (675 aa)    
Predicted Functional Partners:
SLC18B1
MFS-type transporter SLC18B1 isoform X1.
      
 0.893
PANX1
Pannexin 1.
     
0.849
CALHM1
Calcium homeostasis modulator protein 1.
      
 0.631
ARHGEF7
Rho guanine nucleotide exchange factor 7 isoform X1.
      
 0.546
GRIK5
Glutamate receptor ionotropic, kainate 5 isoform X1.
      
 0.518
GP1BB
Platelet glycoprotein Ib beta chain.
      
 0.512
P2RX7
P2X purinoceptor 7 isoform X1.
      
 0.512
HNF1A
Transcription factor 1, hepatocyte nuclear factor 1-alpha.
      
 0.509
ENTPD3
Ectonucleoside triphosphate diphosphohydrolase 3.
      
 0.461
GJB2
Gap junction beta-2 protein.
      
 0.438
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.