Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PANX2Pannexin 2/3. (675 aa)    
Predicted Functional Partners:
PANX1
Pannexin 1.
     
 0.914
SLC18B1
MFS-type transporter SLC18B1 isoform X1.
      
 0.753
POMGNT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2.
      
 0.604
CALHM1
Calcium homeostasis modulator protein 1.
      
 0.544
RIPK4
Receptor interacting serine/threonine kinase 4.
      
 0.492
PTCHD1
Patched domain-containing protein 1.
      
 0.462
NWD2
NACHT and WD repeat domain-containing protein 2 isoform X1.
      
 0.423
GRIK5
Glutamate receptor ionotropic, kainate 5 isoform X1.
      
 0.423
HNF1A
Transcription factor 1, hepatocyte nuclear factor 1-alpha.
      
 0.403
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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