Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SOX9Transcription factor SOX9 (SOX group E). (510 aa)    
Predicted Functional Partners:
RUNX2
Runt-related transcription factor 2 isoform X1.
   
 0.937
PRKACB
CAMP-dependent protein kinase catalytic subunit beta isoform X1.
    
 0.908
PRKACA
CAMP-dependent protein kinase catalytic subunit alpha isoform X1.
    
 0.907
COL2A1
Collagen alpha-1(II) chain isoform X1.
    
 
 0.828
AMH
Muellerian-inhibiting factor.
    
 0.781
FOXL2
Forkhead box protein L2.
    
 0.776
ACAN
Aggrecan core protein isoform X1.
      
 0.775
PAX6
Paired box protein Pax-6 isoform X1.
   
 0.770
PAX7
Paired box 7.
   
 0.769
PAX3
Paired box protein Pax-3-like.
   
 0.750
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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