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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAP43Neuromodulin isoform X1. (242 aa)    
Predicted Functional Partners:
LYPLA2
Acyl-protein thioesterase 2 isoform X1.
     
 0.869
ATF3
Cyclic AMP-dependent transcription factor ATF-3 isoform X1.
   
  
 0.725
TH
Tyrosine 3-monooxygenase.
      
 0.711
STMN2
Stathmin-2.
   
  
 0.684
GFAP
Glial fibrillary acidic protein isoform X1.
   
  
 0.679
SNAP25
Synaptosomal-associated protein 25 isoform X1.
   
  
 0.666
MAP2
Microtubule associated protein 2.
   
 
 0.643
SYP
Synaptophysin.
   
  
 0.638
CNGA2
Cyclic nucleotide-gated olfactory channel.
      
 0.621
ATOH7
Protein atonal homolog 7.
      
 0.614
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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