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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGHMBP2ATP-dependent RNA/DNA helicase IGHMBP2. (984 aa)    
Predicted Functional Partners:
ABT1
Activator of basal transcription 1.
    
 
 0.781
GDAP1
Ganglioside-induced differentiation-associated protein 1 isoform X1.
      
 0.735
BSCL2
BSCL2 lipid droplet biogenesis associated, seipin.
      
 0.628
SH3TC2
SH3 domain and tetratricopeptide repeat-containing protein 2 isoform X1.
      
 0.622
ZC4H2
Zinc finger C4H2 domain-containing protein isoform X1.
      
 0.594
NELFE
Negative elongation factor E.
    
   0.519
RAPSN
43 kDa receptor-associated protein of the synapse isoform X1.
      
 0.518
PIF1
ATP-dependent DNA helicase PIF1.
      
 0.518
TMEM38B
Trimeric intracellular cation channel type B isoform X1.
      
 0.512
LOC109275035
Survival of motor neuron protein.
      
 0.505
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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