Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DEFB123Beta-defensin 123. (83 aa)    
Predicted Functional Partners:
DEFB124
Beta-defensin 124.
     
 0.699
DEFB113
Defensin beta 113.
     
 0.694
ENSPPRP00000000631
annotation not available
     
 0.628
DEFB1
Beta-defensin 1.
     
 0.625
DEFB119
Beta-defensin 119.
     
 0.612
DEFB116
LOW QUALITY PROTEIN: beta-defensin 116.
     
 0.599
DEFB110
Beta-defensin 110.
     
 0.570
DEFB128
Beta-defensin 128.
     
 0.524
DEFB135
Beta-defensin 135.
     
 0.522
ENSPPRP00000003725
annotation not available
    
   0.515
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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