Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MYRFMyelin regulatory factor. (1100 aa)    
Predicted Functional Partners:
SOX10
Transcription factor SOX7/8/10/18 (SOX group E/F).
      
 0.726
SPO11
Meiotic recombination protein SPO11 isoform X1.
    
 
 0.720
OLIG2
Oligodendrocyte transcription factor 2 isoform X1.
      
 0.718
MBP
Myelin basic protein.
      
 0.698
MOK
MAPK/MAK/MRK overlapping kinase isoform X1.
    
 0.656
ICK
Serine/threonine-protein kinase ICK isoform X1.
    
 0.656
MAK
Serine/threonine-protein kinase MAK isoform X1.
    
 0.656
RFFL
E3 ubiquitin-protein ligase rififylin isoform X1.
      
 0.651
GRAMD2B
GRAM domain-containing protein 3.
    
   0.602
PDGFRA
Platelet-derived growth factor receptor alpha.
      
 0.581
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.