Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XRCC3DNA repair protein XRCC3. (350 aa)    
Predicted Functional Partners:
RAD51C
DNA repair protein RAD51 homolog 3.
  
0.998
RAD51
DNA repair protein RAD51 homolog 1.
  
 
0.993
XRCC2
DNA repair protein XRCC2 isoform X1.
   
 0.987
BRCA2
Breast cancer type 2 susceptibility protein isoform X1.
   
 0.979
RAD51D
DNA repair protein RAD51 homolog 4.
    
 0.969
WRN
Werner syndrome ATP-dependent helicase isoform X1.
  
 0.965
RAD51B
DNA repair protein RAD51 homolog 2 isoform X1.
    
0.951
BLM
Bloom syndrome protein isoform X1.
  
 0.947
MUS81
Crossover junction endonuclease MUS81.
   
 0.927
RAD50
DNA repair protein RAD50 isoform X1.
   
 0.927
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.