Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DMAC1Transmembrane protein 261. (112 aa)    
Predicted Functional Partners:
ZNF185
Zinc finger protein 185 isoform X1.
      
 0.592
KLHDC4
Kelch domain-containing protein 4 isoform X1.
      
 0.550
NDUFB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial.
   
 
 0.514
NDUFB7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7.
   
 
 0.498
ARMC7
Armadillo repeat-containing protein 7 isoform X1.
      
 0.496
TMEM186
Transmembrane protein 186.
     
 0.483
NDUFAF5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5.
     
 0.430
NDUFB9
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 isoform X1.
   
 
 0.428
ENSPPRP00000028213
annotation not available
  
 
 0.426
GET3
Arsenite/tail-anchored protein-transporting ATPase.
   
  
 0.422
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (14%) [HD]