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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC110Coiled-coil domain-containing protein 110. (837 aa)    
Predicted Functional Partners:
MED14
Mediator of RNA polymerase II transcription subunit 14.
      
 0.771
SPATA19
Spermatogenesis-associated protein 19, mitochondrial.
   
  
 0.525
ATP2C2
ATPase secretory pathway Ca2+ transporting 2.
      
 0.512
VPS8
Vacuolar protein sorting-associated protein 8 homolog isoform X1.
      
 0.512
IGSF11
Immunoglobulin superfamily, member 11.
      
 0.506
CALR3
Calreticulin 3.
      
 0.501
ZFX
Zinc finger X-chromosomal protein isoform X1.
      
 0.436
COX6B2
Cytochrome c oxidase subunit 6B2.
      
 0.433
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.