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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GJA10Gap junction alpha-10 protein. (491 aa)    
Predicted Functional Partners:
MMS22L
Protein MMS22-like.
      
 0.770
LAMA4
LOW QUALITY PROTEIN: laminin subunit alpha-4.
      
 0.619
AMD1
S-adenosylmethionine decarboxylase proenzyme.
      
 0.596
ENSPPRP00000008538
annotation not available
      
 0.596
LIN28B
Protein lin-28 homolog B isoform X1.
      
 0.517
HMX2
Homeobox protein Nkx-5.
      
 0.513
POU3F1
POU domain, class 3, transcription factor 1.
      
 0.473
ACOT11
Acyl-coenzyme A thioesterase 11 isoform X1.
      
 0.420
ZDHHC9
Palmitoyltransferase ZDHHC9/14/18.
      
 0.420
SARDH
Sarcosine dehydrogenase, mitochondrial isoform X1.
      
 0.418
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.