STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLE2TLE family member 2, transcriptional corepressor. (728 aa)    
Predicted Functional Partners:
NRIP1
Nuclear receptor-interacting protein 1.
     
 0.828
FOXA1
Forkhead box protein A1, hepatocyte nuclear factor 3-alpha.
    
 0.776
EP300
Histone acetyltransferase p300.
    
 0.773
GATA3
Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.
     
 0.751
TCF7
Transcription factor 7.
    
 0.592
TCF7L1
Transcription factor 7 like 1.
    
 0.592
LEF1
Lymphoid enhancer-binding factor 1 isoform X1.
    
 0.592
TCF7L2
Transcription factor 7 like 2.
    
 0.592
TLE1
Transducin-like enhancer protein 1 isoform X1.
  
 
0.534
EN1
LOW QUALITY PROTEIN: homeobox protein engrailed-1.
    
 
 0.525
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.