Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDK20Cyclin-dependent kinase 20. (346 aa)    
Predicted Functional Partners:
CCNH
Cyclin-H isoform X1.
   
 0.888
MNAT1
CDK-activating kinase assembly factor MAT1.
   
 0.860
ERCC2
LOW QUALITY PROTEIN: TFIIH basal transcription factor complex helicase XPD subunit.
    
 0.819
ERCC3
TFIIH basal transcription factor complex helicase XPB subunit.
    
 0.814
LOC109275038
General transcription factor IIH subunit 2 isoform X1.
   
 0.809
GTF2H3
General transcription factor IIH subunit 3 isoform X1.
   
 0.801
POLR2A
LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1.
    
 0.793
GTF2H1
Transcription initiation factor TFIIH subunit 1.
    
 0.788
GTF2E2
Transcription initiation factor IIE subunit beta isoform X1.
   
 0.785
GTF2H4
General transcription factor IIH subunit 4 isoform X1.
    
 0.776
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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