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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK20Cyclin-dependent kinase 20. (346 aa)    
Predicted Functional Partners:
CCNH
Cyclin-H isoform X1.
    
 0.913
MNAT1
CDK-activating kinase assembly factor MAT1.
   
 0.870
GTF2H3
General transcription factor IIH subunit 3 isoform X1.
    
 0.866
ERCC2
LOW QUALITY PROTEIN: TFIIH basal transcription factor complex helicase XPD subunit.
    
 0.864
GTF2E2
Transcription initiation factor IIE subunit beta isoform X1.
   
 0.862
POLR2A
LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1.
    
 0.861
GTF2E1
General transcription factor IIE subunit 1 isoform X1.
    
 0.848
LOC109275038
General transcription factor IIH subunit 2 isoform X1.
   
 0.845
GTF2H1
Transcription initiation factor TFIIH subunit 1.
   
 0.840
ERCC3
TFIIH basal transcription factor complex helicase XPB subunit.
    
 0.836
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.