Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
RNF40E3 ubiquitin-protein ligase BRE1B. (1001 aa)    
Predicted Functional Partners:
RNF20
E3 ubiquitin-protein ligase BRE1A.
  
0.999
WAC
WW domain containing adaptor with coiled-coil.
   
 0.965
UBE2A
Ubiquitin-conjugating enzyme E2 A.
    
 0.921
UBE2B
Ubiquitin-conjugating enzyme E2 B.
    
 0.921
PAF1
RNA polymerase II-associated factor 1 homolog.
    
 0.890
CDC73
Parafibromin isoform X1.
   
 0.845
LEO1
RNA polymerase-associated protein LEO1 isoform X1.
   
 0.815
SETD2
[histone H3]-dimethyl-L-lysine36 N-methyltransferase.
   
 
 0.808
TP53
Cellular tumor antigen p53.
    
 
 0.805
CTR9
RNA polymerase-associated protein CTR9 homolog.
   
 0.780
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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