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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACOT4Acyl-coenzyme A thioesterase 4-like. (420 aa)    
Predicted Functional Partners:
ACOT7
Cytosolic acyl coenzyme A thioester hydrolase isoform X1.
   
 
 0.944
THEM5
Acyl-coenzyme A thioesterase THEM5 isoform X1.
     
 0.940
FBP1
Fructose-1,6-bisphosphatase 1.
   
 0.905
LOC109253800
Acyl-coenzyme A thioesterase 1-like.
  
  
 
0.901
FBP2
Fructose-1,6-bisphosphatase isozyme 2.
   
  0.901
PFKM
ATP-dependent 6-phosphofructokinase, muscle type isoform X1.
     
  0.900
LOC109247758
Very-long-chain enoyl-CoA reductase.
     
 0.900
TECR
LOW QUALITY PROTEIN: very-long-chain enoyl-CoA reductase.
     
 0.900
PFKL
ATP-dependent 6-phosphofructokinase, liver type isoform X1.
     
  0.900
ACOX2
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase.
   
 
 0.576
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.