Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DSTNDestrin (actin-depolymerizing factor). (165 aa)    
Predicted Functional Partners:
CFL1
Cofilin-1 isoform X1.
   
  0.823
ENSPPRP00000003708
annotation not available
   
  0.823
ENSPPRP00000006109
annotation not available
   
  0.823
YWHAE
14-3-3 protein epsilon isoform X1.
   
 
 0.814
CFL2
Cofilin-2.
   
   0.811
LOC109272550
Cofilin-2-like isoform X1.
   
   0.811
WDR1
WD repeat-containing protein 1.
   
 
 0.753
LIMK1
LIM domain kinase 1.
   
 0.715
LIMK2
LIM domain kinase 2 isoform X1.
   
 0.697
SSH2
Protein phosphatase Slingshot homolog 2 isoform X1.
    
 0.667
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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