Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LAPTM5Lysosomal-associated transmembrane protein 5. (263 aa)    
Predicted Functional Partners:
C1QC
Complement C1q subcomponent subunit C.
   
  
 0.994
C1QA
Complement C1q subcomponent subunit A.
   
  
 0.994
LAPTM4B
Lysosomal-associated transmembrane protein 4B.
     
 0.911
LAPTM4A
Lysosomal-associated transmembrane protein 4A.
     
 0.902
CD53
Leukocyte surface antigen CD53.
   
  
 0.887
ITGB2
Integrin beta 2.
   
 
 0.842
HCLS1
Hematopoietic lineage cell-specific protein.
   
    0.819
NEDD4
E3 ubiquitin-protein ligase NEDD4 isoform X1.
    
 
 0.811
LY86
Lymphocyte antigen 86 isoform X1.
   
  
 0.782
NCKAP1L
Nck-associated protein 1-like isoform X1.
   
  
 0.778
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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