Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MTSS1Metastasis suppressor protein 1 isoform X1. (759 aa)    
Predicted Functional Partners:
RAB7A
Ras-related protein Rab-7A.
    
  0.639
SUFU
Suppressor of fused homolog isoform X1.
    
 
 0.537
ZNF572
Zinc finger protein 572.
    
 0.534
ZNF74
Zinc finger protein 74.
    
 0.522
WAS
WASP actin nucleation promoting factor.
    
 0.505
GLI1
Zinc finger protein GLI1 isoform X1.
    
 0.494
MED9
Mediator of RNA polymerase II transcription subunit 9.
    
 
 0.490
PTPN21
Protein tyrosine phosphatase non-receptor type 21.
    
 0.478
TATDN1
TatD DNase domain containing 1.
      
 0.465
WASHC5
WASH complex subunit strumpellin isoform X1.
      
 0.451
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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