STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NR0B2Nuclear receptor subfamily 0 group B member 2. (283 aa)    
Predicted Functional Partners:
NR1H4
Bile acid receptor isoform X1.
   
 0.846
NR5A1
Steroidogenic factor 1.
   
 0.839
NR5A2
Nuclear receptor subfamily 5 group A member 2 isoform X1.
   
 0.839
CYP7A1
Cholesterol 7-alpha-monooxygenase.
    
 0.805
ENSPPRP00000020242
annotation not available
    
 
 0.804
HNF4A
Hepatocyte nuclear factor 4-alpha isoform X1.
   
 0.796
HNF4G
Hepatocyte nuclear factor 4-gamma isoform X1.
   
 0.796
MDM2
E3 ubiquitin-protein ligase Mdm2 isoform X1.
   
 0.776
ESR1
Estrogen receptor isoform X1.
    
 0.725
ABCB11
ATP-binding cassette, subfamily B (MDR/TAP), member 11.
    
 0.722
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.