Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SPEGStriated muscle preferentially expressed protein kinase isoform X1. (3251 aa)    
Predicted Functional Partners:
CUL7
Cullin 7.
   
 0.672
YWHAQ
14-3-3 protein theta isoform X1.
    
   0.666
PES1
Pescadillo homolog isoform X1.
   
 0.649
SYNPO2L
Synaptopodin 2-like protein.
   
 0.640
MTM1
Myotubularin isoform X1.
    
 0.633
WDR18
Pre-rRNA-processing protein IPI3.
   
 0.628
CCDC8
Coiled-coil domain-containing protein 8.
   
 0.618
TEX10
Testis-expressed sequence 10 protein.
   
 0.610
TUT4
Terminal uridylyltransferase 4 isoform X1.
    
 
 0.607
TCAP
Telethonin.
   
 0.601
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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