Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HPNHepsin. (417 aa)    
Predicted Functional Partners:
HGF
Hepatocyte growth factor isoform X1.
    
 0.881
MST1
Hepatocyte growth factor-like protein isoform X1.
    
 0.858
TMPRSS11F
Transmembrane protease serine 11F isoform X1.
    
 
 0.610
SPINT1
Kunitz-type protease inhibitor 1 isoform X1.
    
 0.590
SERPINA5
Plasma serine protease inhibitor isoform X1.
   
 0.583
SPINT2
Kunitz-type protease inhibitor 2.
    
 0.576
PLGRKT
Plasminogen receptor (KT).
    
 
 0.558
SERPINF2
Alpha-2-antiplasmin isoform X1.
   
 0.533
HSD17B2
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+).
   
  
 0.504
AMACR
Alpha-methylacyl-CoA racemase.
   
  
 0.489
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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