Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CSCitrate synthase, mitochondrial isoform X1. (466 aa)    
Predicted Functional Partners:
MDH2
Malate dehydrogenase, mitochondrial.
  
 0.995
ACO2
Aconitate hydratase, mitochondrial isoform X1.
  
 0.995
FH
Fumarate hydratase, mitochondrial.
  
 0.990
GOT2
Aspartate aminotransferase, mitochondrial.
   
 0.989
ACO1
Cytoplasmic aconitate hydratase.
  
 0.989
ACLY
ATP-citrate synthase isoform X1.
  
 0.986
DLAT
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 0.986
SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial.
  
 0.978
IDH3A
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial isoform X1.
  
 0.974
SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1.
  
 0.972
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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