Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPTX2Neuronal pentraxin-2. (431 aa)    
Predicted Functional Partners:
NPAS4
Neuronal PAS domain-containing protein 4 isoform X1.
      
 0.610
GRIA2
Glutamate receptor 2 isoform X1.
    
 
 0.606
RNF2
E3 ubiquitin-protein ligase RNF1/2.
    
 0.574
RING1
E3 ubiquitin-protein ligase RING1 isoform X1.
    
 0.574
EGR1
Early growth response protein 1.
    
 0.571
PCSK1
Proprotein convertase subtilisin/kexin type 1.
      
 0.538
NOL4
Nucleolar protein 4 isoform X1.
   
  
 0.524
PVALB
Parvalbumin alpha.
     
 0.517
EED
Embryonic ectoderm development.
    
 0.506
ANKRD13B
Ankyrin repeat domain-containing protein 13B isoform X1.
      
 0.506
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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