Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM13CProtein FAM13C isoform X1. (502 aa)    
Predicted Functional Partners:
UMODL1
Uromodulin like 1.
      
 0.638
AHCYL1
Adenosylhomocysteinase 2 isoform X1.
    
   0.567
AHCYL2
Adenosylhomocysteinase 3 isoform X1.
    
   0.567
PPP2R3A
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1.
      
 0.543
PPP2R3B
Protein phosphatase 2 regulatory subunit B''beta.
      
 0.543
LOC109259668
Mesothelin-like isoform X1.
      
 0.539
ENSPPRP00000013110
annotation not available
      
 0.523
SDAD1
Protein SDA1 homolog.
      
 0.523
AZGP1
Zinc-alpha-2-glycoprotein isoform X1.
      
 0.478
LOC109263126
Retinol dehydrogenase 12-like isoform X1.
      
 0.467
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (12%) [HD]