Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
REM1RRAD and GEM like GTPase 1. (297 aa)    
Predicted Functional Partners:
FRMPD2
FERM and PDZ domain-containing protein 2 isoform X1.
    
 0.763
CA10
Carbonic anhydrase-related protein 10.
   
  
 0.741
MTOR
Serine/threonine-protein kinase mTOR.
    
 0.689
EGFR
Epidermal growth factor receptor isoform X1.
    
 0.651
ZHX2
Zinc fingers and homeoboxes protein 2.
   
 0.641
GRB2
Growth factor receptor-binding protein 2.
    
 0.637
PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.
    
 0.634
NF1
Neurofibromin 1.
   
 0.621
TSC2
Tuberous sclerosis 2.
    
 0.617
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.615
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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