STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB7Growth factor receptor-bound protein 7 isoform X1. (532 aa)    
Predicted Functional Partners:
ERBB2
Receptor tyrosine-protein kinase erbB-2 isoform X1.
   
 0.975
PTK2
Protein tyrosine kinase 2.
   
 0.845
LAX1
Lymphocyte transmembrane adapter 1 isoform X1.
    
   0.805
RND1
Rho-related GTP-binding protein Rho6.
    
 0.746
ERBB3
Receptor tyrosine-protein kinase erbB-3 isoform X1.
   
 0.743
ERBB4
Receptor tyrosine-protein kinase erbB-4 isoform X1.
   
 0.742
FOXA2
Forkhead box protein A2, hepatocyte nuclear factor 3-beta.
      
 0.739
RET
Proto-oncogene tyrosine-protein kinase receptor Ret.
    
 0.734
TEK
Endothelial-specific receptor tyrosine kinase.
    
 0.703
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.
    
 0.678
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.