STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB7Growth factor receptor-bound protein 7 isoform X1. (532 aa)    
Predicted Functional Partners:
ERBB2
Receptor tyrosine-protein kinase erbB-2 isoform X1.
   
 0.904
TEK
Endothelial-specific receptor tyrosine kinase.
   
 0.800
PDGFRB
Platelet-derived growth factor receptor beta.
    
 0.738
GRB2
Growth factor receptor-binding protein 2.
    
 0.727
ERBB3
Receptor tyrosine-protein kinase erbB-3 isoform X1.
   
 0.679
ERBB4
Receptor tyrosine-protein kinase erbB-4 isoform X1.
   
 0.673
SRC
Proto-oncogene tyrosine-protein kinase Src isoform X1.
   
 0.662
RND1
Rho-related GTP-binding protein Rho6.
    
 0.649
EGFR
Epidermal growth factor receptor isoform X1.
   
 0.639
RET
Proto-oncogene tyrosine-protein kinase receptor Ret.
    
 0.616
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.