Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DOK5Docking protein 5. (306 aa)    
Predicted Functional Partners:
RET
Proto-oncogene tyrosine-protein kinase receptor Ret.
    
 0.666
CIB4
Calcium and integrin binding family member 4.
      
 0.550
ALG14
UDP-N-acetylglucosamine transferase subunit ALG14 homolog isoform X1.
      
 0.523
ANKRD16
Ankyrin repeat domain-containing protein 16 isoform X1.
     
 0.489
VCPIP1
Deubiquitinating protein VCIP135.
      
 0.482
CRK
Adapter molecule crk isoform X1.
    
 0.473
PXDC1
PX domain-containing protein 1.
      
 0.471
WDR6
WD repeat-containing protein 6.
      
 0.466
MUSK
Muscle, skeletal receptor tyrosine-protein kinase.
    
 0.432
CRKL
Proto-oncogene C-crk.
    
 0.425
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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