Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CTSWCathepsin W isoform X1. (374 aa)    
Predicted Functional Partners:
NKG7
Protein NKG7.
   
  
 0.908
BCL2L1
Bcl-2-like 1 (apoptosis regulator Bcl-X).
     
  0.894
BCL2
Apoptosis regulator Bcl-2.
     
  0.894
PRF1
Perforin-1 isoform X1.
   
 
 0.875
BIRC5
Baculoviral IAP repeat-containing protein 5 isoform X1.
     
 0.847
BID
BH3 interacting domain death agonist.
   
 
  0.827
XIAP
E3 ubiquitin-protein ligase XIAP.
     
  0.825
GZMA
Granzyme A.
   
 
 0.782
BIRC2
Baculoviral IAP repeat-containing protein 2/3.
     
 0.774
BIRC3
Baculoviral IAP repeat-containing protein 3-like.
     
 0.774
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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