Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BICC1Protein bicaudal C homolog 1 isoform X1. (974 aa)    
Predicted Functional Partners:
PDGFRA
Platelet-derived growth factor receptor alpha.
   
  
 0.993
SLC35F1
Solute carrier family 35, member F1/2.
      
 0.747
MYRIP
Rab effector MyRIP.
      
 0.708
SDK2
Protein sidekick-2 isoform X1.
      
 0.707
TRIM71
Tripartite motif-containing protein 71.
      
 0.705
PIM3
Proto-oncogene serine/threonine-protein kinase Pim-3.
      
 0.701
ZNF516
Zinc finger protein 516.
      
 0.693
APOLD1
Apolipoprotein L domain-containing protein 1 isoform X1.
      
 0.648
SSX2IP
Afadin- and alpha-actinin-binding protein isoform X1.
   
  
 0.623
CPEB1
Cytoplasmic polyadenylation element-binding protein 1 isoform X1.
   
 
 0.617
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
Server load: low (14%) [HD]