Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CKS2Cyclin-dependent kinase regulatory subunit CKS1. (79 aa)    
Predicted Functional Partners:
SKP2
F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2).
   
 0.876
CCNA2
Cyclin-A2.
   
 0.804
CDK2
Cyclin-dependent kinase 2 isoform X1.
   
 0.799
CDK3
Cyclin-dependent kinase 3-like.
   
 0.769
CCNA1
Cyclin-A1 isoform X1.
   
 0.742
CUL1
Cullin-1 isoform X1.
    
 0.729
RBX1
E3 ubiquitin-protein ligase RBX1.
   
 0.725
CDK1
Cyclin-dependent kinase 1.
   
 0.715
ENSPPRP00000026563
annotation not available
   
 0.715
CCNE2
G1/S-specific cyclin-E2 isoform X1.
   
 0.708
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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