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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC1A2Solute carrier family 1 (glial high affinity glutamate transporter), member 2. (574 aa)    
Predicted Functional Partners:
SLC1A3
Solute carrier family 1 (glial high affinity glutamate transporter), member 3.
  
 
 
0.905
AQP4
Aquaporin-4 isoform X1.
   
  
 0.736
SLC38A2
Solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 2.
    
 
 0.700
SLC7A5
Solute carrier family 7 (L-type amino acid transporter), member 5.
   
 
 0.621
GATA1
Erythroid transcription factor.
      
 0.611
SLC3A2
4F2 cell-surface antigen heavy chain.
   
 
 0.606
SLC38A9
Solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 9.
    
 
 0.603
SLC6A14
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+).
  
  
 0.598
GLUL
Glutamine synthetase isoform X1.
      
 0.588
ENSPPRP00000022236
annotation not available
      
 0.588
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.