Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
UBE2D1Ubiquitin-conjugating enzyme E2 D1 isoform X1. (147 aa)    
Predicted Functional Partners:
ANAPC11
Anaphase-promoting complex subunit 11.
    
 0.990
RBX1
E3 ubiquitin-protein ligase RBX1.
   
 0.973
UBE3A
Ubiquitin-protein ligase E3A isoform X1.
    
 0.968
BARD1
BRCA1-associated RING domain protein 1 isoform X1.
   
 0.967
STUB1
STIP1 homology and U-box containing protein 1.
   
 0.958
RNF7
Ring finger protein 7.
   
 0.955
UBE3C
Ubiquitin-protein ligase E3C isoform X1.
    
 0.951
BRCA1
BRCA1 DNA repair associated.
   
 0.949
RNF4
Ring finger protein 4.
   
 0.948
XIAP
E3 ubiquitin-protein ligase XIAP.
   
 0.944
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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