STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CISD1CDGSH iron-sulfur domain-containing protein 1 isoform X1. (106 aa)    
Predicted Functional Partners:
CISD3
CDGSH iron sulfur domain 3.
   
  
 0.801
PRKN
E3 ubiquitin-protein ligase parkin isoform X1.
    
 
 0.696
DDB1
DNA damage-binding protein 1.
    
 
 0.673
CARS2
Probable cysteine--tRNA ligase, mitochondrial isoform X1.
      
 0.612
TOMM70
Mitochondrial import receptor subunit TOM70.
      
 0.609
USP35
Ubiquitin carboxyl-terminal hydrolase 35/38.
      
 0.581
MIEN1
Migration and invasion enhancer 1.
   
  
 0.567
IREB2
Iron-responsive element-binding protein 2 isoform X1.
   
 
 0.566
BCAP31
B-cell receptor-associated protein 31.
    
   0.558
UBQLN3
Ubiquilin-3-like.
      
 0.549
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.