Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPNS2Sphingolipid transporter 2. (512 aa)    
Predicted Functional Partners:
SPHK2
Sphingosine kinase 2.
     
 0.765
MFSD2B
Major facilitator superfamily domain-containing protein 2B.
     
 0.756
SGPL1
Sphinganine-1-phosphate aldolase.
      
 0.749
SPHK1
Sphingosine kinase 1 isoform X1.
     
 0.747
ENPP2
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X1.
   
 
 0.628
KDSR
3-ketodihydrosphingosine reductase.
     
 0.549
MFSD6L
Major facilitator superfamily domain-containing protein 6-like.
      
 0.539
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.537
ACER1
Alkaline ceramidase 1 isoform X1.
     
 0.511
ACER2
Alkaline ceramidase 2.
     
 0.482
Your Current Organism:
Panthera pardus
NCBI taxonomy Id: 9691
Other names: Leo pardus, P. pardus, leopard
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